Week 6 in the NFL will end with a divisional tilt in Los Angeles on Sunday, October 17, so make sure you check out the best Broncos vs. Chargers betting pick and odds.

Denver and Los Angeles are coming into this divisional battle with certain streaks when they meet at Arrowhead Stadium. Los Angeles won the previous two games, while Denver lost the last two. The Chargers are -4.5 favorites on MyBookie Sportsbook, while the total is set at 45.5 points. These divisional foes have faced on two occasions in 2021, and each team got a win at home.

Nathaniel Hackett’s bad decision cost the Broncos again

The Denver Broncos (2-3, 1-4 ATS) perhaps lost two games in a row, but if they deserved to lose last week in Las Vegas against the Raiders, they certainly were a better side in a 12-9 defeat to the Indianapolis at home. The game went to overtime as the visitor’s scored the game-tying FG, but Denver’s HC Hackett was the one who cost them a tie, at least. He decided to go with 4 & 1 inside the Colts’ five instead of taking an FG.

Russell Wilson completed 21 of 39 passes for 274 yards and two interceptions. One of those picks came late in the game and it affected the outcome. Courtland Sutton and Jerry Jeudy played well with 127 combined yards on eight catches (19 targets). Melvin Gordon III was the best runner with 54 yards on 15 attempts. On defense, Caden Sterns registered a couple of interceptions; Bradley Chubb contributed with 2.5 sacks, while Alex Singleton had a game-high nine tackles.

DE Randy Gregory (knee), CB Ronald Darby (ACL), T Garett Bolles (leg), WR Tim Patrick (knee), CB Michael Ojemudia (elbow), and RB Javonte Williams (knee) are unavailable to play on Monday against the Chargers. S Justin Simmons (quad) and S P.J. Locke III (concussion) are questionable.

Chargers booked a narrow W in Cleveland

The Los Angeles Chargers (3-2, 4-1 ATS) returned to L.A. after a two-game road trip which proved to be successful as they recorded a pair of victories against the Houston Texans and Cleveland Browns. Against the Browns, the Chargers came back from a 14-point deficit to win 30-28. Taylor Bertolet’s field goal in the fourth quarter decided the tilt and helped the Chargers improve to a 3-2 record.

Justin Herbert completed 22 of 34 passes for 228 yards and a touchdown. Austin Ekeler left one yard short of a 200-yard from scrimmage display, but he did find the end zone on that lone TD pass from Herbert. Ekeler also contributed on the ground with 173 yards and a score on 16 carries. Mike Williams was at his usual with 134 yards on ten catches. Defensively, Derwin James Jr. schooled the other defenders with game-high 14 tackles.

DE Joey Bosa (groin) and WR Jalen Guyton (knee) are sidelined and will not play against the Broncos on Monday. WR Keenan Allen (hamstring) and K Dustin Hopkins (quad) are questionable.



•            1-4 ATS in the last five games

•            0-5 ATS in the last five games on the road

•            1-4 ATS in the last five vs. AFC West opponents

Los Angeles:

•            4-1 ATS in the last five games

•            8-3 ATS in the last 11 vs. AFC West rivals

Denver Broncos vs. Los Angeles Chargers Pick  

The Broncos’ defense tried to compensate for the team’s poor offense in previous weeks, but that didn’t work every time. Even though Los Angeles allows 27.2 ppg, which is one of the weakest defenses in the NFL, I don’t think the Broncos are capable of exploiting that fact. Russell Wilson is going through a rough patch, and it looks like this is a losing season for him. I certainly don’t think he will suddenly erupt for a 400-yard, 4-TD game in Los Angeles and turn the world upside down. That’s why I am leaning on Justin Herbert and a solid Chargers offense.

Pick: Take the Chargers at -4.5 (-110)

The Total

I am well aware of the Broncos’ weak offense, but the fact that the Chargers allow around 27 points per game is my best argument to back Over in this one. Denver scored 20+ points only once this season, against the Raiders, another divisional rival, but they did score 20+ in four of the previous six H2H duels, so I am backing the visitors to do it again on Monday. Over is 4-1 in Denver’s previous five games after scoring less than 15 points in their last game; Over is 9-2 in Los Angeles’ last 11 games overall, while Over is 5-1 in the Chargers’ previous six home games.

Pick: Go Over 45.5 points (-110)