San Francisco Giants at San Diego Padres on Wednesday, April 1, 2026 (4:10 PM ET) features Adrian Houser vs. Nick Pivetta. Current line: Padres -154 / Giants +130, Padres -1.5 (+132) vs. Giants +1.5 (-160), total 8.0 (O -110 / U -110).
San Francisco Giants vs San Diego Padres Game Info
| Matchup | San Francisco Giants @ San Diego Padres |
| Date | April 01, 2026 |
| Time | 4:10 PM ET |
| Location | Petco Park (San Diego, CA) |
| How to Watch | NBC Sports Bay Area; Padres.TV (plus MLB.TV out-of-market) |
San Francisco Giants vs San Diego Padres Odds
odds via BetAnything
| Market | Giants | Padres |
|---|---|---|
| Moneyline | +130 | -154 |
| Run Line | +1.5 (-160) | -1.5 (+132) |
| Total | Over 8.0 (-110) | Under 8.0 (-110) |
Team Stats (2026, Year to Date)
| Team | G | R | AVG / OBP / SLG | OPS | Team ERA | WHIP |
|---|---|---|---|---|---|---|
| Giants | 5 | 13 | .215 / .275 / .319 | .594 | 3.40 | 1.09 |
| Padres | 5 | 12 | .182 / .257 / .258 | .515 | 4.60 | 1.40 |
Starting Pitcher Stats
| Pitcher | Hand | 2026 Regular Season | Most Recent Regular-Season Start | 2026 Spring Training (recent) | Key 2025 Note |
|---|---|---|---|---|---|
| Adrian Houser (SF) | RHP | No 2026 regular-season appearances yet | N/A | 3/20: 6.0 IP, 2 ER, 5 K, 2 BB 3/14: 5.0 IP, 2 ER, 6 K, 1 BB 2/25: 2.0 IP, 1 ER, 0 K, 1 BB | 2025: 8-5, 3.31 ERA, 92 K |
| Nick Pivetta (SD) | RHP | 1 GS: 0-1, 18.00 ERA, 3.0 IP, 4 K, 3.33 WHIP | 3/26 vs DET: 3.0 IP, 7 H, 6 ER, 3 BB, 4 K (69 pitches) | 4 Grapefruit League starts: 6.23 ERA (9 ER/13.0 IP) | 2025: 13-5, 2.87 ERA, 181.2 IP, 190 K, 0.99 WHIP |
Recent Form & Pitching Notes
Giants (2-3) — Most recent game: March 31, 2026 (W 9-3 at SD). Logan Webb went 6.0 IP, 3 ER with 4 BB and 5 K (104 pitches). San Francisco only needed 3 bullpen innings: J.T. Brubaker 2.0 scoreless, then Jhony Buttó 1.0 scoreless. Offense finally showed: 16 hits, including a leadoff HR from Willy Adames (4-for-5, HR) and a Matt Chapman HR; Jung Hoo Lee drove in 3.
Padres (1-4) — Most recent game: March 31, 2026 (L 3-9 vs SF). Germán Márquez got hit early: 3.0 IP, 4 ER, 8 H. The pen had to cover 6.0 innings (5 relievers used), and Kyle Hart wore the crooked number (2.1 IP, 4 ER). San Diego’s offense scored all 3 runs in the 3rd (Merrill RBI single, Bogaerts RBI groundout, Andújar RBI single) and didn’t do anything after that.
Betting Trends
- Giants are 2-0 in this series at Petco Park (won 3-2 on March 30; won 9-3 on March 31).
- Giants are 2-0 on the road; Padres are 1-4 overall and 1-4 at home.
- Giants: 13 runs scored through 5 games; Padres: 12 runs scored through 5 games.
- Giants team OPS: .594; Padres team OPS: .515.
- Giants team ERA/WHIP: 3.40 / 1.09; Padres team ERA/WHIP: 4.60 / 1.40.
Breakdown
The market is still pricing San Diego like the better roster, and Pivetta’s ugly 3-inning opener is doing a lot of the heavy lifting for Giants money. The counter is obvious: Pivetta was a frontline arm in 2025, and the Padres need length from him after burning 6 bullpen innings last night.
But you’re also betting on a Padres lineup that’s been ice-cold through five games (.515 team OPS) against a Giants staff that’s thrown strikes and limited damage (3.40 team ERA, 1.09 WHIP). Houser is the unknown (no 2026 regular-season data yet), but his spring work suggests he can at least keep them in the game, and San Francisco’s bullpen is in better shape than San Diego’s entering a day game.
Total 8 is playable to the under: both offenses are sub-.600 OPS, and the Giants/Pads just played a 9-3 game where 4 runs came off one middle-relief appearance (Hart). If Pivetta gives the Padres even average length, this sets up as a lower-scoring, bullpen-managed game.
San Francisco Giants vs San Diego Padres Best Bet
Under 8.0 (-110) (3 out of 5 units)
Both lineups are running on fumes early (.594 Giants OPS, .515 Padres OPS), and this number isn’t accounting enough for a likely Pivetta correction after the opener plus Petco’s run environment.
San Francisco Giants vs San Diego Padres Predicted Score
Our computer projections model for this matchup predicts a final score of San Diego Padres 4, San Francisco Giants 3.